World’s First Baby Born Out Of Womb Transplanted From Dead Donor

World's First Baby Born Out Of Womb Transplanted From Dead Donor

A woman in Brazil who received a womb transplanted from a deceased donor has given birth to a baby girl in the first successful case of its kind, doctors reported.

The case, published in The Lancet medical journal, involved connecting veins from the donor uterus with the recipient’s veins, as well as linking arteries, ligaments and vaginal canals.

It comes after 10 previously known cases of uterus transplants from deceased donors – in the United States, the Czech Republic and Turkey – failed to produce a live birth.

The girl born in the Brazilian case was delivered via caesarean section at 35 weeks and three days, and weighed 2,550 grams (nearly 6 lbs), the case study said.

Dani Ejzenberg, a doctor at Brazil’s Sao Paulo University hospital who led the research, said the transplant – carried out in September 2016 when the recipient was 32 – shows the technique is feasible and could offer women with uterine infertility access to a larger pool of potential donors.

The current norm for receiving a womb transplant is that the organ would come from a live family member willing to donate it.

“The numbers of people willing and committed to donate organs upon their own deaths are far larger than those of live donors, offering a much wider potential donor population,” Ejzenberg said in a statement about the results.

She added, however, that the outcomes and effects of womb donations from live and deceased donors have yet to be compared, and said the technique could still be refined and optimised.

The first baby born after a live donor womb transplant was in Sweden in 2013. Scientists have so far reported a total of 39 procedures of this kind, resulting in 11 live births.

Experts estimate that infertility affects around 10 to 15 percent of couples of reproductive age worldwide. Of this group, around one in 500 women have uterine problems.

Before uterus transplants became possible, the only options to have a child were adoption or surrogacy.

In the Brazilian case, the recipient had been born without a uterus due to a condition called Mayer-Rokitansky-Kuster-Hauser syndrome. The donor was 45 and died of a stroke.


Mirzapur, New Web Series From Amazon Prime Video, Pushes the Envelope in Ways Bollywood Rarely Does

Mirzapur, New Web Series From Amazon Prime Video, Pushes the Envelope in Ways Bollywood Rarely Does

In more ways than one, Mirzapur — Amazon Prime Video’s newest original Web series from India, out now — is a story that isn’t suited for Bollywood’s traditional space: the big screen. None of it has to do with the fact that Mirzapur is an episodic drama, which allows writers to explore characters and chart subplots in manners that isn’t possible on film. Instead, it’s the characteristics and behaviour of those characters, and the level of violence and sex that India’s moral-driven censor board, the CBFC, wouldn’t allow.

“It’s very refreshing because there are very few roles written for women in which their sexuality is acknowledged,” Rasika Dugal, who plays Beena Tripathi, the second wife of the show’s big crime boss in Mirzapur, told Gadgets 360. “We don’t have these conversations about women. Usually, women are objects that have been sexualised, as objects of titillation or as objects of sympathy.”

Also seeMirzapur Offers a Darkly Comedic, Brutal Look at India’s Impoverished Corners

Films from India that have bucked that trend in recent years, the likes of Lipstick Under My Burkha and Veere Di Wedding, can be counted on one hand. Dugal remarked that the scripts she has read for TV shows in the past year have been “far more interesting” than any film scripts she’s read in the past few years. She believes that writers are possibly censoring themselves when it comes to writing for cinema, in contrast to streaming which isn’t regulated by the CBFC.

“Our films are certified in a very, very broad manner: it’s either U, U/A or A,” Ritesh Sidhwani, executive producer on Mirzapur, said. “But there is nothing in between. If you look at TV, you’ve a channel like Discovery Kids, which is only for 9-11-year olds. And there’s a show there, which I was quite surprised to learn, called Little Singham.”

Little Singham is an animated spin-off based on the Ajay Devgn-starrer 2011 action film Singham, which is itself a remake of a 2010 Tamil film. “They started with 60-70 episodes in concept and it’s reached 180-190 episodes,” Sidhwani added. “[That shows] there is an audience for every kind of story. With films, you can go to a 13, 15, and 18 [age bracket], but there shouldn’t be censorship. Beyond 18, once you’re an adult, you can’t tell me to cut something.”

Divyendu Sharma in Amazon Prime Original Series Mirzapur Mirzapur Divyendu Sharma

Divyendu Sharma as Munna Tripathi, Abhishek Banerjee as Compounder in Amazon’s Mirzapur

But until the CBFC gets its act together, stories like Mirzapur‘s will be best told in the streaming domain. In fact, the ideal way to watch even Lipstick Under My Burkha is on Prime Video, which has the film’s uncensored version and not the theatrical release version that was subject to cuts, after originally being denied a release altogether.

That’s not the only way Mirzapur is pushing the envelope. Unlike the majority of filmmaking in India which still relies on ADR (automated dialogue replacement), colloquially known as dubbing, where actors re-record their lines in a studio after filming, Mirzapur made use of sync sound, in which the audio is recorded on location.

“Whenever someone mentions dubbing, I get upset. How will we recreate it in the studio?” Pankaj Tripathi, who plays the show’s central crime figure, Akhandanand Tripathi, asked rhetorically.

“Dubbing, I feel, cheats actors,” Divyendu Sharma, who plays Munna Tripathi, the son of Pankaj’s character on Mirzapur, added. “It’s like, ‘You said it once, now do it again.’ And this time, in a dark room, all alone. It’s so wrong to ask someone to repeat everything. And then, the person on the mic tells you, ‘We’re not getting the right emotion.’ Of course, that’s going to happen. That was filmed in extreme heat, and here I am wearing a sweatshirt in an air-conditioned room. I think it’s a crime to not use of sync sound in this day and age.”

But there’s one aspect that Mirzapur falls short in, technologically. Unlike some Prime Original series from the US, Mirzapur was neither filmed nor mastered in 4K. (Amazon’s previous scripted series from India, Breathe, was notably shot in 8K but received a 2K master.) 4K wasn’t considered for Mirzapur because of two reasons, says Prime Video’s India content chief Vijay Subramaniam, in that not many customers have access to the technology and the post-production infrastructure in India needs to level up.

“We will get there but I don’t think we are there yet,” he added. “Is [4K] important to us? Absolutely.”

mirzapur ritesh sidhwani Mirzapur Ritesh Sidhwani

Ritesh Sidhwani at a press event for Amazon’s Mirzapur
Photo Credit: Chou Chiang/Amazon

From page to screen

Mirzapur comes from the same team behind Amazon’s International Emmy-nominated original series Inside Edge, including producers Farhan Akhtar and Sidhwani, and co-creators Karan Anshuman and Puneet Krishna. The last of those — Krishna — did much of his schooling in the Purvanchal region, the eastern part of Uttar Pradesh the show is based in, which meant he knew people who dealt in the illegal arms and drug business Mirzapur depicts.

None of the on-screen characters are directly based on someone they know, though. “They are all a mélange of many characters and characteristics of many people that we put together,” Anshuman said. “That’s what writers do, right? We steal from real life and make them better.”

And given the large size of the ensemble, Mirzapur is able to paint a vivid, unflinching picture of what life is like in some of India’s most impoverished corners. Anshuman thinks a common theme is “the angst that small-town India is going through, in terms of the aspirations they have, why they can’t fulfil their dreams, and how that goes haywire”.

“And I think we are very, very political in terms of what we stand for, and what our beliefs are,” he added. “The entire writing team — and Ritesh would agree with that — [wanted] to say something beyond just putting a fictional piece out there.”

Mirzapur was part of the original slate that was unveiled at Prime Video’s India launch in late 2016, but having the same creative team as Inside Edge, which premiered in mid-2017, meant it could only go on the floors early this year. Anshuman and Krishna revealed they spent about nine months scripting the first season, going back and forth with Amazon, exchanging drafts and feedback.

“The key here is to accept the fact that the battle is won and lost with the script,” Subramaniam said. “With cinematic TV, you tend to either make it too plot-heavy or not define the motivations of characters as strongly as you need to. But that’s the whole point of the iterative process and we are extremely collaborative.”

Vikrant Massey in Amazon Prime Original Series Mirzapur Vikrant Massey Mirzapur


Kareena Kapoor Khan looks ravishing in this red lace dress from H&M

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What do you think of Kareena Kapoor Khan’s look? (Source: kareena.kapoor.official/Instagram)

Kareena Kapoor Khan can rock almost any look. Whether it is walking down the red carpet or an outing with friends, she never fails to impress with her style. Recently, the actor was seen stepping out for a lunch date with her cousins and she floored the fashion police in a bright red outfit.

The Veere Di Wedding actor looked gorgeous in the simple red lace dress from the brand H&M. Hair tied in a ponytail, the look was rounded out with black sunnies and a red pout. We also liked the black Mansur Gavriel bag she carried and the pair of nude Louboutins she wore with the outfit.

Prior to this, the actor was spotted looking chic and casual in a light blue shirt that featured pink floral applique work on it. She carried the half tucked-in shirt with gigot sleeves effortlessly and teamed it with a pair of blue jeans. The look was accessorised with white heels and was rounded out with light smokey eyes and a neat hairdo